Rapid and Pervasive Changes in Genome-Wide Enhancer Usage During Mammalian Development

Enhancers are distal regulatory elements that can activate tissue-specific gene expression and are abundant throughout mammalian genomes. While substantial progress has been made towards genome-wide annotation of mammalian enhancers, their temporal activity patterns and global contributions in the c...

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Main Authors: Nord, Alex S., Blow, Matthew J., Attanasio, Catia, Akiyama, Jennifer A., Holt, Amy, Hosseini, Roya, Phouanenavong, Sengthavy, Plajzer-Frick, Ingrid, Shoukry, Malak, Afzal, Veena, Rubenstein, John L. R., Rubin, Edward M., Pennacchio, Len A., Visel, Axel
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989111/
https://ncbi.nlm.nih.gov/pubmed/24360275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.033
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