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Close sequence comparisons are sufficient to identify human cis-regulatory elements

Cross-species DNA sequence comparison is the primary method used to identify functional noncoding elements in human and other large genomes. However, little is known about the relative merits of evolutionarily close and distant sequence comparisons. To address this problem, we identified evolutionar...

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Detalhes bibliográficos
Main Authors: Prabhakar, Shyam, Poulin, Francis, Shoukry, Malak, Afzal, Veena, Rubin, Edward M., Couronne, Olivier, Pennacchio, Len A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1484452/
https://ncbi.nlm.nih.gov/pubmed/16769978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.4717506
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