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A novel strategy to identify the location of necessary and sufficient cis-acting regulatory mRNA elements in trypanosomes

Expression of nearly all protein coding genes in trypanosomes is regulated post-transcriptionally, predominantly at the level of mRNA half-life. The identification of cis-acting elements involved in mRNA stability has been hindered by a lack of ability to screen for loss-of-regulation mutants. The m...

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Detalhes bibliográficos
Main Authors: WEBB, HELENA, BURNS, ROISIN, KIMBLIN, NICOLA, ELLIS, LOUISE, CARRINGTON, MARK
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360220/
https://ncbi.nlm.nih.gov/pubmed/15928343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2510505
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