A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron.

Ferritin plays a key role in determining the intracellular fate of iron and is highly regulated by the iron status of the cell. We have identified a cis-acting element in the transcribed but nontranslated 5' leader sequence of human ferritin heavy-chain mRNA. In transiently transfected murine f...

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Detaylı Bibliyografya
Asıl Yazarlar: Hentze, M W, Rouault, T A, Caughman, S W, Dancis, A, Harford, J B, Klausner, R D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1987
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC299157/
https://ncbi.nlm.nih.gov/pubmed/3477805
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