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Synthesis and biological evaluation of γ-aminophosphonates as potent, sub-type selective sphingosine 1-phosphate receptor agonists and antagonists
The synthesis of N-arylamide phosphonates and related arylether and arylamine analogues provided potent, subtype-selective agonists and antagonists of the five known sphingosine 1-phosphate (S1P) receptors (S1P(1–5)). To this end, the syntheses of phosphoserine mimetics - selectively protected and o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1963459/ https://ncbi.nlm.nih.gov/pubmed/17113298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.10.060 |
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