Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall

Several platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) family members display C-terminal protein motifs that confer retention of the secreted factors within the pericellular space. To address the role of PDGF-B retention in vivo, we deleted the retention motif by...

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Bibliographische Detailangaben
Hauptverfasser: Lindblom, Per, Gerhardt, Holger, Liebner, Stefan, Abramsson, Alexandra, Enge, Maria, Hellström, Mats, Bäckström, Gudrun, Fredriksson, Simon, Landegren, Ulf, Nyström, Henrik C., Bergström, Göran, Dejana, Elisabetta, Östman, Arne, Lindahl, Per, Betsholtz, Christer
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2003
Schlagworte:
Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196228/
https://ncbi.nlm.nih.gov/pubmed/12897053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.266803
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