Pericytes limit tumor cell metastasis

Previously we observed that neural cell adhesion molecule (NCAM) deficiency in β tumor cells facilitates metastasis into distant organs and local lymph nodes. Here, we show that NCAM-deficient β cell tumors grew leaky blood vessels with perturbed pericyte-endothelial cell-cell interactions and defic...

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Autors principals: Xian, Xiaojie, Håkansson, Joakim, Ståhlberg, Anders, Lindblom, Per, Betsholtz, Christer, Gerhardt, Holger, Semb, Henrik
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1361347/
https://ncbi.nlm.nih.gov/pubmed/16470244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25705
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