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Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors

Tumor-infiltrating blood vessels deviate morphologically and biochemically from normal vessels, raising the prospect of selective pharmacological targeting. Current antiangiogenic approaches focus mainly on endothelial cells, but recent data imply that targeting pericytes may provide additional bene...

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Detalhes bibliográficos
Main Authors: Abramsson, Alexandra, Lindblom, Per, Betsholtz, Christer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC213487/
https://ncbi.nlm.nih.gov/pubmed/14561699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318549
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