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Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors

Tumor-infiltrating blood vessels deviate morphologically and biochemically from normal vessels, raising the prospect of selective pharmacological targeting. Current antiangiogenic approaches focus mainly on endothelial cells, but recent data imply that targeting pericytes may provide additional bene...

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Autori principali: Abramsson, Alexandra, Lindblom, Per, Betsholtz, Christer
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC213487/
https://ncbi.nlm.nih.gov/pubmed/14561699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318549
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