Physical and functional interactions between polo kinase and the spindle pole component Cut12 regulate mitotic commitment in S. pombe
Commitment to mitosis is regulated by a protein kinase complex called MPF. MPF is inhibited by Wee1-related kinases and activated by Cdc25 phosphatase. MPF activation further boosts Cdc25 and represses Wee1. This feedback control probably involves polo kinase. A dominant cut12.s11 mutation in the Sc...
Zapisane w:
| Wydane w: | Genes Dev |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2003
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12815070/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.256003 |
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