The β-globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation

Lignende værker

• Activation of β-major globin gene transcription is associated with recruitment of NF-E2 to the β-globin LCR and gene promoter
  af: Sawado, Tomoyuki, et al.
  Udgivet: (2001)
• H3 K79 dimethylation marks developmental activation of the β-globin gene but is reduced upon LCR-mediated high-level transcription
  af: Sawado, Tomoyuki, et al.
  Udgivet: (2008)
• The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation
  af: Bender, M. A., et al.
  Udgivet: (2012)
• Flanking HS-62.5 and 3′ HS1, and regions upstream of the LCR, are not required for β-globin transcription
  af: Bender, M. A., et al.
  Udgivet: (2006)
• The murine β-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes
  af: Schübeler, Dirk, et al.
  Udgivet: (2001)