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The β-globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation

To investigate the molecular basis of β-globin gene activation, we analyzed factor recruitment and histone modification at the adult β-globin gene in wild-type (WT)/locus control region knockout (ΔLCR) heterozygous mice and in murine erythroleukemia (MEL) cells. Although histone acetylation and meth...

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Bibliografske podrobnosti
Main Authors: Sawado, Tomoyuki, Halow, Jessica, Bender, M.A., Groudine, Mark
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC196035/
https://ncbi.nlm.nih.gov/pubmed/12672691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1072303
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