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The β-globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation
To investigate the molecular basis of β-globin gene activation, we analyzed factor recruitment and histone modification at the adult β-globin gene in wild-type (WT)/locus control region knockout (ΔLCR) heterozygous mice and in murine erythroleukemia (MEL) cells. Although histone acetylation and meth...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196035/ https://ncbi.nlm.nih.gov/pubmed/12672691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1072303 |
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