Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments

Pax5-deficient progenitor B (pro-B) cells are thought to be severely defective for recombination of all immunoglobulin heavy chain (IgH) V gene segments, but the mechanism by which Pax5 regulates this process has not been defined. To address this issue, we have examined the assembly of the IgH locus...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Hesslein, David G.T., Pflugh, David L., Chowdhury, Dipanjan, Bothwell, Alfred L. M., Sen, Ranjan, Schatz, David G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2003
Assuntos:	Research Communication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC195966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12514097/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1031403
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!