Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments
Pax5-deficient progenitor B (pro-B) cells are thought to be severely defective for recombination of all immunoglobulin heavy chain (IgH) V gene segments, but the mechanism by which Pax5 regulates this process has not been defined. To address this issue, we have examined the assembly of the IgH locus...
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| Yayımlandı: | Genes Dev |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC195966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12514097/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1031403 |
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