Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments

Pax5-deficient progenitor B (pro-B) cells are thought to be severely defective for recombination of all immunoglobulin heavy chain (IgH) V gene segments, but the mechanism by which Pax5 regulates this process has not been defined. To address this issue, we have examined the assembly of the IgH locus...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Genes Dev
Autori principali:	Hesslein, David G.T., Pflugh, David L., Chowdhury, Dipanjan, Bothwell, Alfred L. M., Sen, Ranjan, Schatz, David G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2003
Soggetti:	Research Communication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC195966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12514097/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1031403
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!