CASPASE-3- AND CALPAIN-MEDIATED TAU CLEAVAGE ARE DIFFERENTIALLY PREVENTED BY ESTROGEN AND TESTOSTERONE IN BETA-AMYLOID-TREATED HIPPOCAMPAL NEURONS

A growing body of evidence suggests that the proteolytic cleavage of the microtubule-associated protein tau, the main component of neurofibrillary tangles, might play a role in the molecular mechanisms underlying beta-amyloid (Aβ)-induced neurotoxicity in central neurons. In the present study, we an...

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Hlavní autoři: Park, So-Young, Tournell, Caryn, Sinjoanu, Roxana C., Ferreira, Adriana
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955430/
https://ncbi.nlm.nih.gov/pubmed/17055174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2006.09.012
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