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Role of Gα(12) and Gα(13) as Novel Switches for the Activity of Nrf2, a Key Antioxidative Transcription Factor
Gα(12) and Gα(13) function as molecular regulators responding to extracellular stimuli. NF-E2-related factor 2 (Nrf2) is involved in a protective adaptive response to oxidative stress. This study investigated the regulation of Nrf2 by Gα(12) and Gα(13). A deficiency of Gα(12), but not of Gα(13), enh...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952151/ https://ncbi.nlm.nih.gov/pubmed/17591699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02065-06 |
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