Role of Gα(12) and Gα(13) as Novel Switches for the Activity of Nrf2, a Key Antioxidative Transcription Factor

Gα(12) and Gα(13) function as molecular regulators responding to extracellular stimuli. NF-E2-related factor 2 (Nrf2) is involved in a protective adaptive response to oxidative stress. This study investigated the regulation of Nrf2 by Gα(12) and Gα(13). A deficiency of Gα(12), but not of Gα(13), enh...

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Bibliografiske detaljer
Main Authors: Cho, Min Kyung, Kim, Won Dong, Ki, Sung Hwan, Hwang, Jong-Ik, Choi, Sangdun, Lee, Chang Ho, Kim, Sang Geon
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952151/
https://ncbi.nlm.nih.gov/pubmed/17591699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02065-06
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