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Tripping a Switch: PDZRhoGEF rgRGS-Bound Gα13
Ras superfamily guanine nucleotide-binding proteins, such as G-proteins and small GTPases, are a paradigm for two-state molecular switches in cell signaling. Recent experimental and theoretical studies question this simple model. Now Chen et al. (2008) provide evidence that the rgRGS domain of PDZRh...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782408/ https://ncbi.nlm.nih.gov/pubmed/18940599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.09.003 |
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