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Tripping a Switch: PDZRhoGEF rgRGS-Bound Gα13

Ras superfamily guanine nucleotide-binding proteins, such as G-proteins and small GTPases, are a paradigm for two-state molecular switches in cell signaling. Recent experimental and theoretical studies question this simple model. Now Chen et al. (2008) provide evidence that the rgRGS domain of PDZRh...

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Autors principals: Hamaneh, Mehdi Bagheri, Buck, Matthias
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782408/
https://ncbi.nlm.nih.gov/pubmed/18940599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.09.003
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