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p53 Mediates Senescence-Like Arrest Induced by Chronic Replicational Stress

Previous studies have shown that exposure of cells to high levels of replicational stress leads to permanent proliferation arrest that does not require p53. We have examined cellular responses to therapeutically relevant low levels of replicational stress that allow limited proliferation. Chronic ex...

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Detalhes bibliográficos
Principais autores: Marusyk, Andriy, Wheeler, Linda J., Mathews, Christopher K., DeGregori, James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952086/
https://ncbi.nlm.nih.gov/pubmed/17515610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01316-06
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