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p53 Mediates Senescence-Like Arrest Induced by Chronic Replicational Stress

Previous studies have shown that exposure of cells to high levels of replicational stress leads to permanent proliferation arrest that does not require p53. We have examined cellular responses to therapeutically relevant low levels of replicational stress that allow limited proliferation. Chronic ex...

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Bibliografische gegevens
Hoofdauteurs: Marusyk, Andriy, Wheeler, Linda J., Mathews, Christopher K., DeGregori, James
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952086/
https://ncbi.nlm.nih.gov/pubmed/17515610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01316-06
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