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REPLICATIONAL STRESS SELECTS FOR P53 MUTATION

p53 is a critical mediator of cellular responses to a variety of stresses. Given the frequency of p53 mutations in human malignancies and that disruption of p53 has been implicated in chemoresistance, understanding the factors that select for p53 disruption is important both for understanding tumor...

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Hlavní autoři: Marusyk, Andriy, DeGregori, James
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394679/
https://ncbi.nlm.nih.gov/pubmed/17786047
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