Heptose I Glycan Substitutions on Neisseria gonorrhoeae Lipooligosaccharide Influence C4b-Binding Protein Binding and Serum Resistance

Lipooligosaccharide (LOS) heptose (Hep) glycan substitutions influence gonococcal serum resistance. Several gonococcal strains bind the classical complement pathway inhibitor, C4b-binding protein (C4BP), via their porin (Por) molecule to escape complement-dependent killing by normal human serum (NHS...

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Main Authors: Ram, Sanjay, Ngampasutadol, Jutamas, Cox, Andrew D., Blom, Anna M., Lewis, Lisa A., St. Michael, Frank, Stupak, Jacek, Gulati, Sunita, Rice, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Molecular Pathogenesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952009/
https://ncbi.nlm.nih.gov/pubmed/17526744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01109-06
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