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X-Ray Crystal Structures of Human Immunodeficiency Virus Type 1 Protease Mutants Complexed with Atazanavir

Atazanavir, which is marketed as REYATAZ, is the first human immunodeficiency virus type 1 (HIV-1) protease inhibitor approved for once-daily administration. As previously reported, atazanavir offers improved inhibitory profiles against several common variants of HIV-1 protease over those of the oth...

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Bibliografiske detaljer
Main Authors: Klei, Herbert E., Kish, Kevin, Lin, Pin-Fang M., Guo, Qi, Friborg, Jacques, Rose, Ronald E., Zhang, Yaqun, Goldfarb, Valentina, Langley, David R., Wittekind, Michael, Sheriff, Steven
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951392/
https://ncbi.nlm.nih.gov/pubmed/17537865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02503-05
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