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Molecular Basis for Increased Susceptibility of Isolates with Atazanavir Resistance-Conferring Substitution I50L to Other Protease Inhibitors

Protease inhibitors (PIs) are highly effective drugs against the human immunodeficiency virus (HIV), yet long-term therapeutic use is limited by emergence of HIV type 1 (HIV-1) protease substitutions that confer cross-resistance to multiple protease inhibitor drugs. Atazanavir is a highly potent HIV...

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Bibliografische gegevens
Hoofdauteurs: Yanchunas, Joseph, Langley, David R., Tao, Li, Rose, Ronald E., Friborg, Jacques, Colonno, Richard J., Doyle, Michael L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195399/
https://ncbi.nlm.nih.gov/pubmed/16127059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3825-3832.2005
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