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Differential Requirements of NS4A for Internal NS3 Cleavage and Polyprotein Processing of Hepatitis C Virus

The NS3 protein of hepatitis C virus (HCV) possesses protease activity responsible for the proteolytic cleavage of the viral polyprotein at the junctions of nonstructural proteins downstream of NS3. The NS3 protein was also found to be internally cleaved. In this study, we demonstrated that internal...

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Autori principali: Kou, Yi-Hen, Chang, Ming-Fu, Wang, Yi-Ming, Hung, Tzu-Min, Chang, Shin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951333/
https://ncbi.nlm.nih.gov/pubmed/17522200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00348-07
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