Differential Requirements of NS4A for Internal NS3 Cleavage and Polyprotein Processing of Hepatitis C Virus

The NS3 protein of hepatitis C virus (HCV) possesses protease activity responsible for the proteolytic cleavage of the viral polyprotein at the junctions of nonstructural proteins downstream of NS3. The NS3 protein was also found to be internally cleaved. In this study, we demonstrated that internal...

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Detaylı Bibliyografya
Asıl Yazarlar: Kou, Yi-Hen, Chang, Ming-Fu, Wang, Yi-Ming, Hung, Tzu-Min, Chang, Shin C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Genome Replication and Regulation of Viral Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951333/
https://ncbi.nlm.nih.gov/pubmed/17522200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00348-07
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