Dehydroepiandrosterone upregulates soluble guanylate cyclase and inhibits hypoxic pulmonary hypertension

OBJECTIVE: It has been reported that dehydroepiandrosterone is a pulmonary vasodilator and inhibits chronic hypoxia-induced pulmonary hypertension. Additionally, dehydroepiandrosterone has been shown to improve systemic vascular endothelial function. Thus, we hypothesized that chronic treatment with...

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Bibliografiske detaljer
Main Authors: Oka, Masahiko, Karoor, Vijaya, Homma, Noriyuki, Nagaoka, Tetsutaro, Sakao, Eiko, Golembeski, Scott M, Limbird, Jennifer, Imamura, Masatoshi, Gebb, Sarah A, Fagan, Karen A, McMurtry, Ivan F
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950784/
https://ncbi.nlm.nih.gov/pubmed/17346686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardiores.2007.01.021
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