GSK-3β Controls Osteogenesis through Regulating Runx2 Activity

Despite accumulated knowledge of various signalings regulating bone formation, the molecular network has not been clarified sufficiently to lead to clinical application. Here we show that heterozygous glycogen synthase kinase-3β (GSK-3β)-deficient mice displayed an increased bone formation due to an...

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Bibliografski detalji
Glavni autori: Kugimiya, Fumitaka, Kawaguchi, Hiroshi, Ohba, Shinsuke, Kawamura, Naohiro, Hirata, Makoto, Chikuda, Hirotaka, Azuma, Yoshiaki, Woodgett, James R., Nakamura, Kozo, Chung, Ung-il
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2007
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950686/
https://ncbi.nlm.nih.gov/pubmed/17786208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000837
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