GSK-3β Controls Osteogenesis through Regulating Runx2 Activity

Despite accumulated knowledge of various signalings regulating bone formation, the molecular network has not been clarified sufficiently to lead to clinical application. Here we show that heterozygous glycogen synthase kinase-3β (GSK-3β)-deficient mice displayed an increased bone formation due to an...

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Détails bibliographiques
Auteurs principaux: Kugimiya, Fumitaka, Kawaguchi, Hiroshi, Ohba, Shinsuke, Kawamura, Naohiro, Hirata, Makoto, Chikuda, Hirotaka, Azuma, Yoshiaki, Woodgett, James R., Nakamura, Kozo, Chung, Ung-il
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2007
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950686/
https://ncbi.nlm.nih.gov/pubmed/17786208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000837
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