GSK-3β Controls Osteogenesis through Regulating Runx2 Activity

Despite accumulated knowledge of various signalings regulating bone formation, the molecular network has not been clarified sufficiently to lead to clinical application. Here we show that heterozygous glycogen synthase kinase-3β (GSK-3β)-deficient mice displayed an increased bone formation due to an...

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Dettagli Bibliografici
Autori principali: Kugimiya, Fumitaka, Kawaguchi, Hiroshi, Ohba, Shinsuke, Kawamura, Naohiro, Hirata, Makoto, Chikuda, Hirotaka, Azuma, Yoshiaki, Woodgett, James R., Nakamura, Kozo, Chung, Ung-il
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950686/
https://ncbi.nlm.nih.gov/pubmed/17786208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000837
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