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A unique error signature for human DNA polymerase ν

Human DNA polymerase ν is one of three A family polymerases conserved in vertebrates. Although its biological functions are unknown, pol ν has been implicated in DNA repair and in translesion DNA synthesis (TLS). Pol ν lacks intrinsic exonucleolytic proofreading activity and discriminates poorly aga...

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Hlavní autoři: Arana, Mercedes E., Takata, Kei-ichi, Garcia-Diaz, Miguel, Wood, Richard D., Kunkel, Thomas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950682/
https://ncbi.nlm.nih.gov/pubmed/17118716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2006.09.012
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