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A Novel Alkylating Agent, Glufosfamide, Enhances the Activity of Gemcitabine In vitro and In vivo

Glufosfamide is an alkylating agent consisting of iphosphoramide mustard conjugated to glucose that is currently included in clinical studies of pancreatic cancer. We studied the effects of glufosfamide, in combination with gemcitabine, on in vitro and in vivo models of pancreatic cancer. In prolife...

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Autori principali: Ammons, W Steve, Wang, Jin-Wei, Yang, Zhijian, Tidmarsh, George F, Hoffman, Robert M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950432/
https://ncbi.nlm.nih.gov/pubmed/17786181
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