Pomalidomide enhanced gemcitabine and nab-paclitaxel on pancreatic cancer both in vitro and in vivo

BACKGROUND: Chemotherapy with gemcitabine and nab-paclitaxel (gemcitabine/nab-paclitaxel) is recommended for unresectable pancreatic cancer. However, the therapeutic efficacy is attenuated by the antitumor agent-induced activation of nuclear factor-κB (NF-κB). Thalidomide inhibits NF-κB activation,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Saito, Nobuhiro, Shirai, Yoshihiro, Uwagawa, Tadashi, Horiuchi, Takashi, Sugano, Hiroshi, Haruki, Koichiro, Shiba, Hiroaki, Ohashi, Toya, Yanaga, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884664/
https://ncbi.nlm.nih.gov/pubmed/29644009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24608
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