Pomalidomide promotes chemosensitization of pancreatic cancer by inhibition of NF-κB

INTRODUCTION: Nuclear factor κB (NF-κB) plays an important role in cancer progression and causes therapeutic resistance to chemotherapy. Pomalidomide, a third-generation immunomodulating drug derived from thalidomide, has been approved for uncontrolled multiple myeloma. We hypothesized that pomalido...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shirai, Yoshihiro, Saito, Nobuhiro, Uwagawa, Tadashi, Shiba, Hiroaki, Horiuchi, Takashi, Iwase, Ryota, Haruki, Koichiro, Ohashi, Toya, Yanaga, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880604/
https://ncbi.nlm.nih.gov/pubmed/29632644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24577
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