Glycogen synthase kinase‐3β activity plays a key role in the antitumor effect of nafamostat mesilate in pancreatic cancer cells

Pancreatic cancer is often resistant to chemotherapy. We previously showed the efficacy of combination treatment using gemcitabine and nafamostat mesilate (FUT‐175) for patients with unresectable pancreatic cancer. However, the mechanisms that affect the sensitivity of FUT‐175 are not fully understo...

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Detalhes bibliográficos
Publicado no:Ann Gastroenterol Surg
Main Authors: Haruki, Koichiro, Shiba, Hiroaki, Shimada, Yohta, Shirai, Yoshihiro, Iwase, Ryota, Fujiwara, Yuki, Uwagawa, Tadashi, Ohashi, Toya, Yanaga, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868870/
https://ncbi.nlm.nih.gov/pubmed/29863120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ags3.12025
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