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The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2

The Mdm2 oncoprotein forms a complex with the p53 tumor suppressor protein and inhibits p53-mediated regulation of heterologous gene expression. Recently, Mdm2 has been found to bind several other proteins that function to regulate cell cycle progression, including the E2F-1/DP1 transcription factor...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Jones, Stephen N., Sands, Arthur T., Hancock, Amy R., Vogel, Hannes, Donehower, Lawrence A., Linke, Steven P., Wahl, Geoffrey M., Bradley, Allan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The National Academy of Sciences of the USA 1996
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC19502/
https://ncbi.nlm.nih.gov/pubmed/8943068
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