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Frequent Hypermethylation of the hMLH1 Gene Promoter in Differentiated-Type Tumors of the Stomach with the Gastric Foveolar Phenotype

Hypermethylation of the hMLH1 mismatch repair gene promoter has been revealed to lead to microsatellite instability (MSI). Previously, we demonstrated a high prevalence of MSI in differentiated-type gastric tumors showing distinct features of gastric foveolar epithelium (foveolar type). To clarify t...

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Detalhes bibliográficos
Main Authors: Endoh, Yasushi, Tamura, Gen, Ajioka, Yoichi, Watanabe, Hidenobu, Motoyama, Teiichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949419/
https://ncbi.nlm.nih.gov/pubmed/10980110
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