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Promoter Methylation Status of E-Cadherin, hMLH1, and p16 Genes in Nonneoplastic Gastric Epithelia

Silencing of tumor suppressor and tumor-related genes by hypermethylation at promoter CpG islands is one of the major events in human tumorigenesis. Promoter methylation is also present in nonneoplastic cells as an age-related tissue-specific phenomenon that precedes the development of neoplasia. To...

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Bibliografske podrobnosti
Main Authors: Waki, Takayoshi, Tamura, Gen, Tsuchiya, Takashi, Sato, Kiyoshi, Nishizuka, Satoshi, Motoyama, Teiichi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850716/
https://ncbi.nlm.nih.gov/pubmed/12163364
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