Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia

While chromosomal instability is a common feature of human solid tumours, no abnormalities in genes involved in the mitotic checkpoint have been identified. However, recently, Chfr (checkpoint with forkhead associated and ring finger), a mitotic stress checkpoint gene, has been reported to be inacti...

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Bibliographic Details
Main Authors: Honda, T, Tamura, G, Waki, T, Kawata, S, Nishizuka, S, Motoyama, T
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2004
Subjects:
Genetics and Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409474/
https://ncbi.nlm.nih.gov/pubmed/15138487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601849
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