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Hypermethylation of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia
A number of tumor suppressor and tumor-related genes exhibit promoter hypermethylation with resultant gene silencing in human cancers. The frequencies of methylation differ among genes and genomic regions within CpG islands in different tissue types. Hypermethylation initially occurs at the edge of...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Baishideng Publishing Group Co., Limited
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999099/ https://ncbi.nlm.nih.gov/pubmed/21160773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4251/wjgo.v1.i1.41 |
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