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Hypermethylation of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia

A number of tumor suppressor and tumor-related genes exhibit promoter hypermethylation with resultant gene silencing in human cancers. The frequencies of methylation differ among genes and genomic regions within CpG islands in different tissue types. Hypermethylation initially occurs at the edge of...

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Bibliografiske detaljer
Hovedforfatter: Tamura, Gen
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Co., Limited 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999099/
https://ncbi.nlm.nih.gov/pubmed/21160773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4251/wjgo.v1.i1.41
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