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Lack of CD47 on nonhematopoietic cells induces split macrophage tolerance to CD47(null) cells
Macrophages recognize CD47 as a marker of “self” and phagocytose CD47(null) hematopoietic cells. Using CD47 chimera models, here, we show that the phagocytic activity of macrophages against CD47(null) hematopoietic cells is conferred by CD47 expression on nonhematopoietic cells, and this “education”...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1949343/ https://ncbi.nlm.nih.gov/pubmed/17699632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702881104 |
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