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Attenuation of phagocytosis of xenogeneic cells by manipulating CD47
Signal regulatory protein α (SIRPα) is a critical immune inhibitory receptor on macrophages, and its interaction with CD47, a ligand for SIRPα, prevents autologous phagocytosis. We hypothesized that interspecies incompatibility of CD47 may contribute to the rejection of xenogeneic cells by macrophag...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1785095/ https://ncbi.nlm.nih.gov/pubmed/17008545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-019794 |
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