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Genetic Evidence for a Role of BiP/Kar2 That Regulates Ire1 in Response to Accumulation of Unfolded Proteins

In the unfolded protein response (UPR) signaling pathway, accumulation of unfolded proteins in the endoplasmic reticulum (ER) activates a transmembrane kinase/ribonuclease Ire1, which causes the transcriptional induction of ER-resident chaperones, including BiP/Kar2. It was previously hypothesized t...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kimata, Yukio, Kimata, Yuki I., Shimizu, Yusuke, Abe, Hiroshi, Farcasanu, Ileana C., Takeuchi, Masato, Rose, Mark D., Kohno, Kenji
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC194903/
https://ncbi.nlm.nih.gov/pubmed/12808051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-11-0708
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