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Structural and Energetic Aspects of Grb2-SH2 Domain-Swapping

The SH2 domain of growth factor receptor-bound protein 2 (Grb2) has been the focus of numerous studies, primarily because of the important roles it plays in signal transduction. More recently, it has emerged as a useful protein to study the consequences of ligand preorganization upon energetics and...

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Détails bibliographiques
Auteurs principaux: Benfield, Aaron P., Whiddon, Benjamin B., Clements, John H., Martin, Stephen F.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1947945/
https://ncbi.nlm.nih.gov/pubmed/17466257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.03.010
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