Absence of the β subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the α(1) subunit and eliminates excitation-contraction coupling

The multisubunit (α(1S), α(2)/δ, β(1), and γ) skeletal muscle dihydropyridine receptor transduces transverse tubule membrane depolarization into release of Ca(2+) from the sarcoplasmic reticulum, and also acts as an L-type Ca(2+) channel. The α(1S) subunit contains the voltage sensor and channel por...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gregg, Ronald G., Messing, Albee, Strube, Caroline, Beurg, Maryline, Moss, Richard, Behan, Mary, Sukhareva, Manana, Haynes, Susan, Powell, Jeanne A., Coronado, Roberto, Powers, Patricia A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19477/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943043/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.13961
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