Absence of the β subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the α(1) subunit and eliminates excitation-contraction coupling

The multisubunit (α(1S), α(2)/δ, β(1), and γ) skeletal muscle dihydropyridine receptor transduces transverse tubule membrane depolarization into release of Ca(2+) from the sarcoplasmic reticulum, and also acts as an L-type Ca(2+) channel. The α(1S) subunit contains the voltage sensor and channel por...

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Detalles Bibliográficos
Autores principales: Gregg, Ronald G., Messing, Albee, Strube, Caroline, Beurg, Maryline, Moss, Richard, Behan, Mary, Sukhareva, Manana, Haynes, Susan, Powell, Jeanne A., Coronado, Roberto, Powers, Patricia A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1996
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC19477/
https://ncbi.nlm.nih.gov/pubmed/8943043
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