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Functional analysis of a frame-shift mutant of the dihydropyridine receptor pore subunit (α(1S)) expressing two complementary protein fragments
BACKGROUND: The L-type Ca(2+) channel formed by the dihydropyridine receptor (DHPR) of skeletal muscle senses the membrane voltage and opens the ryanodine receptor (RyR1). This channel-to-channel coupling is essential for Ca(2+) signaling but poorly understood. We characterized a single-base frame-s...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC64647/ https://ncbi.nlm.nih.gov/pubmed/11806762 |
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