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Sequence Determinants of E2-E6AP Binding Affinity and Specificity
The conjugation of ubiquitin to substrates requires a series of enzymatic reactions consisting of an activating enzyme (E1), conjugating enzymes (E2) and ligases (E3). Tagging the appropriate substrate with ubiquitin is achieved by specific E2-E3 and E3-substrate interactions. E6AP, a member of the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1945100/ https://ncbi.nlm.nih.gov/pubmed/17433363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.03.026 |
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