Загрузка...

Proteasome-dependent endoplasmic reticulum-associated protein degradation: An unconventional route to a familiar fate

Until recently, the degradation of aberrant and unassembled proteins retained in the endoplasmic reticulum (ER) was thought to involve unidentified ER-localized proteases. We now show that the ER-associated degradation (ERAD) of two mutant proteins that accumulate in the ER lumen is inhibited in a p...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Werner, Eric D., Brodsky, Jeffrey L., McCracken, Ardythe A.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences of the USA 1996
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC19430/
https://ncbi.nlm.nih.gov/pubmed/8943015
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!