Proteasome-dependent endoplasmic reticulum-associated protein degradation: An unconventional route to a familiar fate
Until recently, the degradation of aberrant and unassembled proteins retained in the endoplasmic reticulum (ER) was thought to involve unidentified ER-localized proteases. We now show that the ER-associated degradation (ERAD) of two mutant proteins that accumulate in the ER lumen is inhibited in a p...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943015/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.13797 |
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