Učitavanje...
Role of CD28 in fatal autoimmune disorder in scurfy mice
Scurfy mice develop CD4 T-cell–mediated lymphoproliferative disease leading to death within 4 weeks of age. The scurfy mutation causes loss of function of the foxp3 gene (foxp3(sf)), which is essential for development and maintenance of naturally occurring regulatory CD4 T cells (nTregs). In humans,...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1939901/ https://ncbi.nlm.nih.gov/pubmed/17463170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-054585 |
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