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CD4(+)CD25(+) Regulatory T Cells Resist a Novel Form of CD28- and Fas-Dependent p53-Induced T Cell Apoptosis

Ag receptor stimulation of preactivated T cells causes rapid cell death in an IL-2– and Fas-dependent manner. This phenomenon, known as activation-induced cell death (AICD), plays a pivotal role in the removal of Ag-reactive T cells after initial expansion. In this study, we report a novel form of T...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Singh, Nagendra, Yamamoto, Mutsumi, Takami, Mariko, Seki, Yoichi, Takezaki, Mayuko, Mellor, Andrew L., Iwashima, Makio
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436589/
https://ncbi.nlm.nih.gov/pubmed/19949106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900753
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