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D-β-Hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
Parkinson disease (PD) is a neurodegenerative disorder characterized by a loss of the nigrostriatal dopaminergic neurons accompanied by a deficit in mitochondrial respiration. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that causes dopaminergic neurodegeneration and a mitocho...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2003
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193668/ https://ncbi.nlm.nih.gov/pubmed/12975474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318797 |
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